Sang-Kyu Lee ¹, Cheong-Hwan Lim ², Hong-Ryang Jung ², Mi-Ja Park ³, Jae-Yong Lee ⁴

Affiliations
1 Department of Radiation Oncology, Yonsei Cancer Center, KR
2 Department of Radiological Science, Hanseo University, KR
3 Department of Health Administration, Dangjin Health City, KR
4 Department of Computer Engineering, Hanseo University, KR

Abstract

Objectives: In the radiation therapy of cancer that occurs in hepatobiliary system, we want to compare and study the usefulness of the method to minimize movement of tumor by using artificially respiratory control device (Abdominal Compressor: AC) and the inducing respiratory control equipment (Abches System: AS). Methods/Statistical Analysis: For the purpose of the present study, analysis is conducted by acquiring images of free breathing(FB), artificially AC and inducing AS respectively of 30 patients. Findings:Results of the analysis to the subjects in 3 specific groups Analysis results of 3 patients groups according to the movement of tumor controlled by three methods is the following. Average ITV and PTV are reduced in AC and AS group by 42.0% and 32.6% respectively. In reproducibility, the variation values are lateral (RL) direction (X) -0.28 ± 0.65mm, vertical (SI) direction (Y) 0.02 ± 1.22mm, and (AP) direction (Z) 0.29 ± 1.55mm. Among the three-target-groups of patients, the maximum error occurs in FS which are side (RL) direction (X) -0.77 ± 1.65mm, vertical (SI) direction (Y) 0.05 ± 3.4mm, and (AP) direction (Z) 5.7 ± 2.86mm so that AC and AS group have less error and better reproducibility. Statistical analysis on tumor volume (ITV,PTV) of 3 specific group shows reduction of volume in respiratory control group. The most reduction is in AC apply from 1468.3±446.8 cc in FB to 757.7±210.3 cc in AC((p<0.00). Application/Improvements: In conclusion, radiation therapy is to protect normal tissues, with the aim of suppressing tumors so the motion associated with respiration during radiation therapy is minimized. Fractionated radiation therapy and high dose 1 fraction radiation therapy demands great reproducibility and appropriate respiratory control for site- specific tumor needs to be considered.

Keywords

Radiotherapy, Reproducibility, Respiration, Tom therapy.

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Kim Ki-Oh ¹, Cheong-Hwan Lim ¹, Cheong-Hwan Lim ¹, Lee Doo Hyun ², Lee Doo Hyun ², Hong-Ryang Jung ¹, Hong-Ryang Jung ¹, Mi-Ja Park ³, Mi-Ja Park ³, Jae-Yong Lee ⁴, Jae-Yong Lee ⁴

Affiliations
1 Department of Radiological Science, Hanseo University, KR
2 Department of Proton Center, National Cancer Center, KR
3 Department of Health Administration, Dangjin Health City, KR
4 Department of Computer Engineering, Hanseo University, KR

Abstract

Background/Objectives: When receiving radiation treatment in form of tomotherapy, most head and neck cancer patients show symptoms of weight loss caused by stomatitis and esophagitis, and skin burns. Weight loss may lead to a closer distance between the skin and the target, causing a change in the measured skin dose. This study was conducted to analyze such changes during the radiation treatment period. Methods/Statistical Analysis: The study also analyzed whether factors such as patient gender, age, diagnosis type, and treatment regimen, including surgery or chemotherapy in addition to radiotherapy, might influence the weight changes in patients, and collected values for changes in skin dose using thermoluminescence dosimeters. Findings: The study considered 20 patients with head and neck cancer, and all of these patients showed weight loss and an increase in measured skin dose. In addition, the gender or age of the patients had no direct relationship with their weight changes. Patients who hadn't undergone surgery prior to concurrent chemotherapy and radiation therapy showed a substantial weight loss. In comparison, the patients who had undergone surgery prior to concurrent chemotherapy and radiation therapy displayed the least amount of weight loss. As the amount of weight loss became larger, so did the skin dose that was measured during tomotherapy (p<.05). Application/Improvements: It appeared that greater weight loss led to an increase in measured skin dose, From this study, it is implied patients with large weight loss may benefit with an adjustment of their radiotherapy parameters while maintaining their target doses.

Keywords

Chemotherapy, Thermoluminescence Dosimeter, Tomotherapy, Surgery, Weight Loss.

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